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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name hsa-miR-26a
ncRNA Category miRNA
Disease name diabetic retinopathy (DR)
Species Homo sapiens
Tissues/Cell_line human RPE ARPE-19
Methods CCK-8 assay, flow cytometry, DCFH-DA staining, qRT-PCR, Western blot
Expression pattern up-regulated
Functional description Rg1 protected ARPE-19 cells against HG-induced injury through up-regulating miR-26a, along with inhibition of the ERK and Wnt/β-catenin pathways.
PubMed ID 30763577
Year 2019
Title Ginsenoside Rg1 protects human retinal pigment epithelial ARPE-19 cells from toxicity of high glucose by up-regulation of miR-26a.
Drug-related ncRNA YES (Ginsenoside Rg1)

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